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SYNOZ® (1% hyaluronic acid sodium salt)

SYNOZ® is a medical device containing 1% sodium salt of hyaluronic acid for intra-articular use. The product is a sterile, isotonic, viscoelastic solution for intra-articular use, in the form of a ready-to-use pre-filled syringe. Final steam sterilization ensures 100% sterility.

The product is a medical device intended for injections into the synovial (knee, hip, ankle, shoulder) joints in humans in order to restore the natural viscoelasticity of the synovial fluid (viscosupplementation). It is indicated for the treatment of pain and reduced mobility of the joint resulting from degenerative changes or injuries of the synovial joint (ostearthrosis).

The product is a sterile, isotonic, viscoelastic solution for intra-articular use in the form of a ready-to-use syringe. One ready-to-use syringe contains 2 ml of viscoelastic solution. 1 ml of the product contains 10 ml (1%) of sodium hyaluronate, sodium chloride, sodium hydrogen phosphate, citric acid and water for injections. The product is sterile and intended for single use only. The product is steam sterilized in a blister. No animal derived materials are used in the production process; they are also not used as raw materials. The product does not contain pharmacologically active substances.

The solution contains hypoallergenic hyaluronic acid obtained by bacterial fermentation from bacteria and Streptococcus equi.

Concentration: 10 mg / ml (1%) sodium hyaluronate.
The 2 ml syringe contains 20 mg of hyaluronic acid.

Indications:
SYNOZ® may be administered to the selected joint depending on the needs of the individual patient, the area and the pathology to be treated.

Application possibilities:

  •  osteoarthritis (osteoarthritis),
  • pain ailments and limitations of joint mobility, resulting from joint injuries or overloads,
  • other, according to assessment of the attending physician and the patient’s condition.

Application method:
Depending on the size of the joint, a maximum of 2 ml of the product can be administered intraarticularly. In the case of the knee, hip, ankle and shoulder joints, 3 to 5 injections are recommended at weekly intervals. Treatment can be carried out on several joints at the same time and the treatment cycles can be repeated.

Pharmaceutical form

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